Calculation of Relative Risk of CML Patients

Created by: Baccarani (Project 4) , generated 2006/03/29, last changed: 2006/12/27

Das Feld der Genomik und Proteomik beinhaltet Schlüsseltechnologien wie das "Gene und Protein Expression Profiling".

CHRONIC MYELOID LEUKEMIA CALCULATION OF RELATIVE RISK (RR)
Age:	years
Spleen:	max. distance from costal margin cm x 10 (e.g. 6 cm = 60)
Platelet:	Plt 10⁹ L ( e.g 350000 ml = 350 )
Blood Basophils:	% x 10 ( e.g. 1.5% = 15 )
Blood Eosinophils:	% x 10 ( e.g 2.6% = 26 )
Blood Myeloblasts:	% x 10 ( e.g 0.7% = 7 )


Sokal RR:
Hasford RR:


Sokal JE et al, Blood 1984; 63: 789-799 Hasford J et al, JNTL Cancer Inst 1998; 90: 850-858
Notice Spleen size, platelet count and differential must be measured and performed before any treatment No calculation should be made to assess the RR of pretreated or late chronic phase patients

EUTOS for CML is a unique collaboration between the European LeukemiaNet and Novartis Oncology in Europe