Disease(s)
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Eosinophilia associated chronic myeloproliferative disorders (e. g. idiopathic hypereosinophilic syndrome, chronic eosinophilic leukemia, atypical chronic myeloid leukemia with eosinophilia, systemic mastocytosis with eosinophilia)
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Leader(s) of the study group
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Prof. J. Apperley
Imperial College School of Medicine
Hammersmith Hospital London, UK
j.apperley@ic.ac.uk
Prof. G. Martinelli
Institute of Hematology and Medical Oncology "L. and A. Seràgnoli. University of Bologna, Via Massarenti, 9-40138 Bologna, Italy. gmartino@kaiser.alma.unibo.it
Dr. A. Reiter
III. Medizinische Universitätsklinik, Klinikum Mannheim der Universität Heidelberg, Wiesbadener Str. 7-11, 68305 Mannheim. Germany
andreas.reiter@med3.ma.uni-heidelberg.de
Prof. N. C. P. Cross
Wessex Regional Genetics Laboratories, Salisbury, U.K. & Human Genetics Research Division, University of Southampton School of Medicine, Southampton, UK
ncpc@soton.ac.uk
Prof. Saglio
Division of Hematology and Internal Medicine, Department of Clinical and Biological Sciences of the University of Turin, 10043 Orbassano-Turin, Italy.
giuseppe.saglio@unito.it
Dr. J. Cools
Flanders Interuniversity Institute for Biotechnology, Leuven, Belgium
jan.cools@med.kuleuven.ac.be
Dr. D. Cilloni
Division of Hematology and Internal Medicine, Department of Clinical and Biological Sciences of the University of Turin, 10043 Orbassano-Turin, Italy.
daniela.cilloni@unito.it
Prof. C. Preudhomme
Laboratoire d'Hématologie A, Hôpital Calmette-CHU of Lille, France; Unité INSERM-U524-Lille
cpreudhomme@chru-lille.fr
Dr. A. Sureda
Clinical Hematology Division, Hospital de la Santa Creu i Sant Pau, St Antoni Maria Claret, 167, 08025 Barcelona, Spain.
asureda@hsp.santpau.es
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Studies
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Italy
Imatinib in HES (Principal investigator: Prof. G. Martinelli, Bologna, see above)
Germany
Evaluation of the efficacy, safety and tolerability of imatinib mesylate (Glivec ) in patients with idiopathic hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL) and systemic mastocytosis with eosinophilia (SME). (Phase II).
(Principal investigator: PD Dr. A. Reiter, Mannheim, see above)
UK
Contact person: Prof. J. Apperley, London, see above
(for shortprotocols, see studies)
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Diagnostic Labs
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Prof. Dr. N.C.P. Cross
Wessex Regional Cytogenetics Centre, Salisbury, United Kingdom.
ncpc@soton.ac.uk
PD Dr. A. Reiter
III. Medizinische Universitätsklinik, Klinikum Mannheim der Universität Heidelberg, Wiesbadener Str. 7-11, 68305 Mannheim, Germany
andreas.reiter@med3.ma.uni-heidelberg.de
Prof. Dr. Saglio
Division of Hematology and Internal Medicine, Department of Clinical and Biological Sciences of the University of Turin, 10043 Turin, Italy.
saglio@csi.it
Dr. J. Cools
Flanders Interuniversity Institute for Biotechnology, Leuven, Belgium
jan.cools@med.kuleuven.ac.be
Prof. Dr. C. Preudhomme
Laboratoire d'Hématologie A, Hôpital Calmette-CHU of Lille, France; Unité INSERM-U524-Lille
cpreudhomme@chru-lille.fr
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