Created by: Hellenbrecht (ELIC) , generated 2006/02/14, last changed: 2011/10/26
The main objective of this workpackage is to integrate the leading European national trial groups in CML to form a cooperative network for advancements in CML related research and health care. A clinical trials platform was created to promote the performance of clinical trials with new drugs and/or treatment strategies across Europe. Standardization of diagnostic and therapeutic procedures allows to compare outcome across Europe. On the basis of uniform common data sets a registry of newly diagnosed CML patients within trials was set up. Standardized molecular and advanced genomic technology to analyze biological prognostic factors, MRD, resistance to therapy and progressive disease across Europe was applied to CML.
On the basis of randomized clinical trials metaanalyses will be performed. Metaanalyses, consensus reports and expert reviews will be used to develop guidelines on a European scale. Spread of excellence will be achieved by regular meetings, training courses, exchange of researchers and information through the internet and printed media.